The CDASHIG MS domain is used to represent data from drug susceptibility testing performed on collected biological specimens, This includes phenotypic testing (i.e., drug is added directly to a culture of organisms) and genotypic tests that provide results in terms of susceptible or resistant. Drug susceptibility testing may occur on a wide variety of non-host organisms, including bacteria, viruses, fungi, protozoa, and parasites. Phenotypic drug susceptibility testing may involve determining susceptibility/resistance (qualitative) at a defined concentration of antibiotic or sponsor drug, or may involve determining a specific dose (quantitative) at which a drug inhibits organism growth or some other process associated with virulence (e.g., minimum inhibitory concentration, MIC). The MS domain is appropriate for both of these types of drug susceptibility tests.
The current Controlled Terminology for MSTESTCD assumes that the test may not be agent-specific but points to a broader use of the overall MSTESTCD/MSTEST as defined in the most current version of CT.
Local Processing - In this scenario, biological specimens are taken and analyzed, and the results are recorded directly on the CRF.
This example is for a COVID test. The user will need to update the questions, as appropriate.