Are there QRS-like instruments for which the collected data would not be stored in the FT, QS, or RS domains?

Yes, certain Clinical Classifications may be stored in other domains. The rule for storing Clinical Classifications is:

If the instrument is a Rating or Grading Scale in which the intent of the instrument is to evaluate a single body system, then it would be stored in the morphology/physiology domain which represents that body system (see TAUG-RA: Swollen Joint Count/Tender Joint Count Example). Other Rating or Grading Scales related to multiple body systems and all Composite Score type instruments would be represented as a Clinical Classification in the RS domain. If the data is based on microscopic data, those type of scoring instruments would be represented in the MI domain (see the PrCa-TAUG Pathology 2 – Gleason example).

• Composite types of instruments provide an assessment based on multiple individual assessments that can be represented in other domains. For example, the APACHE II is a composite instrument that has a CRF and would be stored as a Clinical Classification in the RS domain because it has a variety of labs, respiratory, and vital sign assessments in addition to the Glasgow Coma Score. This variety of data is scored separately in the APACHE II instrument. This composite scoring approach is currently represented as a Clinical Classification in the RS domain.
• Another type of Clinical Classification that is stored in the RS domain deals with the rating of symptoms or other medical conditions related to multiple body systems. These are not posed as a questionnaire with specific questions and specific answers, but have CRFs with the symptoms or medical conditions listed with a specific rating scale that is evaluated by an examiner.
• Rating and Grading Scales are instruments that may or may not use observations from multiple body systems, but there is no CRF with a place for the individual assessments' values and therefore no calculation of an overall score. For example, TIMI Grade is a grading system for coronary blood flow that has no CRF and is based on the CV body system.  This Grading Scale instrument is related to a single body system and would be stored in the related morphology/physiology body system domain.